Advances in migraine genetics, neurobiology and treatment

Written by Siobhan Bennett (Future Science Group)

Migraines are one of the most prevalent neurological disorders and are ranked the seventh most disabling disease globally [1]. They are estimated to affect 12–20% of the adult population and are more prevalent than diabetes, epilepsy and asthma combined [1–2]. Despite previous misconceptions, the most common being that migraines are a “bad headache”, a migraine is a sensory processing defect within the brain. This affects how the brain deals with incoming information, causing normally harmless inputs to be painful [3–4]. Over the past decade, the understanding of migraine pathophysiology has significantly advanced. Improved characterization and diagnosis of the symptoms have...

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