Advances in migraine genetics, neurobiology and treatment
Migraines are one of the most prevalent neurological disorders and are ranked the seventh most disabling disease globally [1]. They are estimated to affect 12–20% of the adult population and are more prevalent than diabetes, epilepsy and asthma combined [1–2]. Despite previous misconceptions, the most common being that migraines are a “bad headache”, a migraine is a sensory processing defect within the brain. This affects how the brain deals with incoming information, causing normally harmless inputs to be painful [3–4]. Over the past decade, the understanding of migraine pathophysiology has significantly advanced. Improved characterization and diagnosis of the symptoms have...