In this interview, we spoke with Alysson Muotri about defining cell maturity in brain organoids and how we could address the challenges with these systems.
Browsing: Development and pediatrics
Neonatologists have determined that there may be links between disruption of placental allopregnanolone delivery to the fetus and brain injuries associated with autism.
Researchers have demonstrated that cerebral organoids grown at the air–liquid interface are able to generate nerve tracts and stimulate muscle output; these could be used to improve understanding of neurological diseases such as dementia.
A recent study has indicated that vitamin D affects perineuronal nets within the brain, which could facilitate the loss of brain plasticity.
This week we look at gammaCore™ for cluster headache, warnings of stroke risk with a multiple sclerosis drug and a gene therapy for spinal muscular atrophy.
The EMA has approved Gilenya® (fingolimod) for the treatment of children and adolescents with relapsing–remitting forms of multiple sclerosis.
A team of researchers have devised a novel method of diagnosing autism in children. Following analysis of short home videos of children, mathematical modelling was utilized to provide a numerical score indicating the severity of the developmental disorder.
Research presented at SfN has provided insight into the neural risks and benefits of marijuana use, including development and Alzheimer’s disease.
Three studies have been highlighted at SfN Neuroscience on the links between adolescent brain development, mental health and substance abuse.
Gene therapy for disorders such as amyotrophic lateral sclerosis, Parkinson’s disease and Batten disease has seen success in animal models.