CCFv3: high-resolution 3D atlas of the mouse brain developed

Written by Alice Bough (Future Science Group)

Credit: Allen Institute for Brain Science

Researchers from the Allen Institute for Brain Science (WA, USA) have manually constructed a 3D reference atlas of the entire mouse brain. The map, named the Allen Mouse Brain Common Coordinate Framework (CCFv3), allows the user to navigate the average brain of a mouse on a cellular level. Standard reference atlases of the mouse brain have generally been 2D, and while useful, these cannot be used for informatics-based workflows or data visualization. There are some 3D atlases but these have low resolution, which limits their use in large-scale data generation efforts. “Modern digital reference atlases must evolve to stay current,”...

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