Dementia-on-a-chip: Trevor Bushell and Michele Zagnoni on microfluidics, collaboration and the future of dementia research

Written by Lauren Pulling, Editor

The use of on-a-chip technologies has seen enormous growth across the biomedical sciences in recent years, but how can this approach be harnessed to further understand dementia and its contributing diseases, and develop new therapies? We spoke to Trevor Bushell and Michele Zagnoni (both University of Strathclyde, UK) about how they’ve brought together their respective expertise in neuroscience and bioengineering to develop “dementia-on-a-chip” microfluidic technologies. In this interview, they discuss their joint projects, including how they’re enabling predictions on the efficacy and pharmacological effects of agents targeting tau in Alzheimer’s disease; the importance of collaboration; and their forecast for the...

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