Dementia with Lewy bodies therapy may be improved by addition of seizure drug

Written by Roisin Conneely

Combining an established seizure drug with current dementia with Lewy bodies (DLB) medication may be an effective way to bring about mobility improvements whilst minimizing negative psychiatric side effects, according to research from the National Center of Neurology and Psychiatry (Tokyo, Japan). DLB is the second most common type of dementia, after Alzheimer’s disease, but current therapy largely relies on the Parkinson’s disease drug, levodopa. The drug is used to treat mobility symptoms in DLB but often leads to worsening of psychiatric symptoms, such as hallucinations and delusions. The study, published in Neurology, followed 158 DLB patients who had been...

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