Further roles of Rbfox1 in autism identified

Written by Alice Weatherston

New research carried out at the University of California, Los Angeles (UCLA; CA, USA) has uncovered further roles of Rbfox1, a gene known to be linked to the development of autism. The findings were published recently in Neuron and could provide new avenues for treatment targets for the disorder. “Before we can develop an effective therapy to target a gene, we must first understand how the gene operates in the cell,” commented principal investigator Kelsey Martin (UCLA). Study coauthor, Daniel Geschwind (UCLA), and colleagues previously linked mutations in Rbfox1 to an increased risk of autism development. By collaborating with UCLA...

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