High-inflammation depression linked to reduced functional connectivity

Written by Alice Weatherston

Increased levels of inflammation have previously been identified in approximately one third of individuals diagnosed with depression. A recent study published in Molecular Psychiatry has explored this association more fully and suggests that persistent inflammation has a direct impact on areas of the brain associated with long-term and often difficult to treat symptoms of depression, such as anhedonia. The study, which was carried out by a team of researchers based at Emory University School of Medicine (GA, USA) and Winship Cancer Institute (GA, USA), collected MRI data from 48 patients with a depression diagnosis, in order to analyze functional connectivity....

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