Plain Language Summary: Sodium oxybate improved symptoms in people with narcolepsy
Narcolepsy is a disease that affects about 1 in 2000 people. People with narcolepsy experience periods of extreme sleepiness during the day. Some also experience cataplexy, which is a sudden muscle weakness usually triggered by an emotion like laughter or surprise.
This is a plain language summary of an article originally published in the journal Sleep. Once-nightly sodium oxybate (ON-SXB for short; also known as FT218) is a potential treatment for excessive daytime sleepiness and cataplexy. The US FDA is deciding whether to approve ON-SXB to be prescribed to adults with narcolepsy. The REST-ON clinical study looked at whether ON-SXB was better than a placebo at treating narcolepsy symptoms.
