Potential marker of non-reversible brain damage following concussion identified

Written by Alice Weatherston

A new study carried out at the University of Pennsylvania (PA, USA) and the University of Glasgow (Glasgow, UK) has highlighted increases in the protein termed alpha II-spectrin N-terminal fragment (SNTF), following mild traumatic brain injury, (mTBI) as a potential marker of diffuse axonal injury, a specific type of brain damage often associated with cognitive impairments. The findings were published recently in Acta Neuropathologica and suggest that blood tests detecting SNTF could one day provide a method for diagnosing diffuse axonal injury and predicting cognitive impairment in concussion patients. SNTF was identified as a potential biomarker by the study team...

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