Recent meta-analysis suggests a neurochemical difference between anxiety disorders in humans

Written by Louise White

A meta-analysis carried out by researchers from the University of São Paulo (Brazil), Imperial College London (UK), University of Western Australia (Perth, Australia) and the University of Toronto (ON, Canada), that aimed to evaluate the role of serotonin in various anxiety disorders, has indicated that previous disorder groupings may not be accurate based on serotonergic functioning. Using data pooled from six studies of remitted fear/anxiety patients exposed to syndrome-specific aversive stimulation under acute tryptophan depletion, the team evaluated whether results supported Deakin and Graeff’s previously published theory of the dual role of serotonin in response to varying threats. The results...

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