Steadying your nerves: innovation for repairing peripheral nerve injuries
Hydrogel scaffolds can be used to guide mesenchymal stem cells derived from gingival tissue to develop into pro-regenerative cells, repairing peripheral nerve injury with the same effectiveness as an autograft.
A cross-disciplinary team from the University of Pennsylvania School of Dental Medicine and Perelman School of Medicine (PA, USA) combined gingiva-derived mesenchymal stem cells (GMSCs) with a 3D collagen hydrogel scaffold to enable the functional recovery of nerves following peripheral nerve injury (PNI).
