Among chronic neurodegenerative disorders, Parkinson’s disease (PD) is one of the most difficult and challenging to tackle as several motor and nonmotor features influence the patients’ quality of life (QoL) and daily activities. Assessing patients QoL with valid instruments and gathering knowledge about the determinants that affect QoL in individuals with PD are the basis of an efficient caring strategy. In addition to the known motor symptoms, nonmotor disorders must also be comprehensively tracked and targeted for treatment to enhance QoL. A holistic strategy to maintain QoL in people with PD should consist of a multidisciplinary, personalized and patient-centered approach with timely administration of palliative care and efficient involvement of caregivers and family members.
Parkinson’s disease (PD) is the second most common neurodegenerative disorder, affecting seven to ten million people worldwide with an average onset age of 60 years old. Following the global trend of population aging, the disability-adjusted life years for PD has increased to 22.9% during 2005–2013 . PD has been for long known mainly for its cardinal movement-related symptoms such as bradykinesia, resting tremor, rigidity and postural disturbances. However, it is now clear that though highly various in timing and severity, people with PD (PwP) also suffer from numerous nonmotor symptoms (NMSs) such as psychiatric manifestations (depression, anxiety), constipation, hyposmia, autonomic dysfunctions (orthostatic hypotension, urinary symptoms), sleep disorders, cognitive impairment, fatigue and pain .
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