Supplement may promote remyelination in multiple sclerosis patients

Written by Ellen Clarke

Researchers have found that the vitamin D receptor promotes the differentiation of oligodendrocyte progenitor cells and enhances myelin sheath regeneration. The findings could lead to new remyelination enhancing drugs for multiple sclerosis patients and those suffering from other demyelinating diseases. Multiple sclerosis patients experience continuous loss of the myelin that insulates neurons in the central nervous system. Oligodendrocyte progenitor cells (OPCs) migrate towards neurons and differentiate into myelin producing oligodendrocytes in response to demyelination, however this process slows as a person ages. Retinoid X receptor gamma (RXR-ɣ) is a nuclear receptor protein that is known to promote OPC differentiation and...

To view this content, please register now for access

It's completely free