Epilepsy linked to structural abnormalities in multiple brain regions

Written by Roisin Conneely

Researchers from UCL (London, UK) and the Keck School of Medicine, USC (CA, USA) have linked epilepsy to structural abnormalities in several regions of the brain. The study highlights more widespread physical changes associated with the disease than have ever previously been described, even in idiopathic generalized epilepsy, characterized by its lack of observable changes in the brain. The team took brain structural measurements from MRI scans of 2149 epilepsy patients, compared with 1727 healthy controls. The trial was conducted by the global ENIGMA-Epilepsy consortium, combining data from 24 research centers across 14 countries throughout Europe, Asia, Australia and North...

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