Original Publication Date: >3 August, 2015
Publication / Source: Regenerative Medicine
Authors: Mandi J Corenblum, Andrew J Flores, Michael Badowski, David T Harris & Lalitha Madhavan
Aim: Here we investigated the neuroprotective potential of systemic CD34+ human cord blood cells (hCBCs) in a 6-hydroxydopamine rat model of Parkinson’s disease. Methods: Purified CD34+ hCBCs were intravenously administered to rats subjected to 6-hydroxydopamine 24 h earlier, and behavioral and immunohistological analysis performed.