Neurology Central

A new perspective on the development of neural circuits in embryos


It is still not fully understood how undefined cells travel to reach their final location within an embryo and specialize to their specific roles when forming neural circuits.

“There are lots of things we’re guessing are happening that we don’t actually see,” commented Yinan Wan, a researcher at the Howard Hughes Medical Institute’s Janelia Research Campus (VA, USA).

Therefore, in a recent study published in the journal Cell, Wan and her colleagues tracked the developmental origins, movement and functional activity of all neurons as they formed neural circuits in zebrafish.

It took the team 7 years to develop the technology that records and collects data from developing neurons and it was the first time that scientists could do this in live animals.

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