Neurology Central

Could microdoses of lithium halt progression of Alzheimer’s disease in rats?


The value of lithium therapy in the treatment Alzheimer’s disease has remained a controversy in the field as the information gathered to date has been acquired using a multitude of differential approaches, conditions, formulation, timings and doses of treatment, leading to results that are difficult to compare. 

In a recent study, which has been published in the Journal of Alzheimer’s Disease, a team of researchers from McGill University (Montreal, Canada) has revealed that lithium in doses up to 400-times lower than what is currently being prescribed for mood disorders is capable of halting signs of advanced Alzheimer’s pathology (e.g., amyloid plaques) and recovering lost cognitive abilities in rats.

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