3D printed transparent skull grants insight into Alzheimer’s disease development

Written by Georgi Makin (Future Science Group)

Neurofibrillary tangles in pyramidal neurons of the human cerebral cortex a distinctive neuropathological feature of Alzheimer s disease AD detected through the silver carbonate method

Research published in Nature Communications describes how a research team from the University of Minnesota (MN, USA) has designed a 3D printed, transparent implant to fit the skull of a mouse, creating a ‘window’ for real-time monitoring of the surface of the brain. The device could allow for unique research opportunities into a variety of neurological conditions, including concussions as well as Alzheimer’s and Parkinson’s diseases. Traditionally, the focus of research groups in these areas has been to examine small, isolated regions of the brain. More recently, however, researchers are finding that events occurring in some areas of the brain...

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