Boosting fluorescent sensors to get a WIFF of successful glioblastoma treatment
Researchers enhance the signal emitted by fluorescing nanosensors, improving the signal-to-noise ratio by 50-fold, allowing for deep tissue detection.
Fluorescent sensors can be used to label and image a variety of molecules in living cells; however, the fluorescent signal is lost if the sensors are implanted too deep into tissues. To overcome this, researchers from the Massachusetts Institute of Technology (MIT; MA, USA) have developed a novel photonic technique (a technique using light waves) for exciting any fluorescent sensor, thereby improving the resulting signal.