Epigenetic genes linked to multiple sclerosis risk in large-scale study

Scientists at the Technical University of Munich and the Max Planck Institute of Psychiatry (both Munich, Germany) have conducted a genome-wide association study on multiple sclerosis (MS) susceptibility. This led to the discovery of four new risk genes that were modified in patients with MS, indicating that these genes, which govern epigenetic processes, may play a part in the cellular mechanisms in MS development. The study was published in the journal Science Advances. As the cause of MS is not yet understood, this new discovery of the four risk genes, termed L3MBTL3, MAZ, ERG and SHMT1, may facilitate a better...