Future biomaterials for enhanced cell–substrate communication in spinal cord injury intervention

Written by Pradeep Kumar

Neuro(bio)platforms, the extracellular matrix mimicking support structures formed and fabricated from biomaterials, constitute an inherent component of the regenerative strategies employed in neuro-trauma and -degeneration interventions. The choice of these bioplatforms is dependent on several physico-chemical and -mechanical characteristics of the constituent biomaterial(s) which in turn defines the intent (biocompatibility) and extent (biodegradability) of their stay in the neuroenvironment. These factors and features are further essential to realize the complex neuromimetic network formation capable of inherent axonal regeneration with no external mediation. This paradigm develops into an even more complex setting when such archetypes are loaded and seeded with biofactors...

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