Global, genome-wide glioma study identifies new genetic risk factors
An international consortium of researchers from 14 cancer centers has conducted the largest study to-date searching for genetic markers of glioma. It is estimated that approximately 24,000 people will be diagnosed with malignant brain tumors in the USA in 2017, with 17,000 deaths. Glioblastoma, the most common form of malignant brain tumor, has a 5-year survival rate of under 6%. Genome-wide association analysis has improved our understanding of glioma susceptibility; however, studies to-date have had limited power in identifying risk loci. To address this, the collaborative research team analyzed genetic variants from 12,496 individuals with glioma, and 18,190 without. The...
