Most cited and most notorious: how the 2006 Alzheimer’s paper potentially misled research

Written by Beatrice Bowlby (Future Science Group)

Data included in a pivotal Alzheimer’s study from 2006 may have been fabricated, potentially misleading research for the last 16 years.  

Physician and neuroscientist Matthew Schrag (Vanderbilt University, TN, USA) raised concern about the validity of a research paper published in 2006 regarding the primary role of amyloid-beta (Aβ) plaques in causing the neurodegenerative disease, Alzheimer’s. This important paper served as the scientific basis for the development of an anti-Aβ plaque drug, called Simufilam, by Cassava Sciences (TX, USA).

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