Multiple sclerosis: determining the dynamic nature of oligodendrocyte regeneration

Written by Alice Bough (Future Science Group)

A team of researchers from The Karolinska Institute (Stockholm, Sweden) and from Uppsala University (Uppsala, Sweden) have utilized radiocarbon dating to determine that neurogenesis of myelin-producing cells in people living with multiple sclerosis (MS) is limited. The paper, which has been published in Nature, highlights the importance of detecting and treating MS at an early stage in its progression. Previous studies in rodents have demonstrated that lost myelin can be regenerated, a process requiring the generation of new oligodendrocytes. It was considered that this generation of new cells occurred in the remission stages of MS progression. In this study, the...

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