Myelination replicated in brain organoids

Researchers from the Case Western Reserve University School of Medicine (OH, USA) have developed a method for creating brain organoids with oligodendrocytes included, building on previous research by the New York Stem Cell Foundation (NYSCF) Research Institute (NY, USA), allowing them to study diseases related to myelination in a more accurate cellular environment than ever before. Organoids provide a useful cellular environment for studying disease progression, and for testing treatments. However, the lack of oligodendrocytes in brain organoids has, until now, prevented detailed research on conditions such as multiple sclerosis or spinal cord injury. In a collaborative study published in...