Could novel cell sequencing methods map the cellular origins of brain disorders?

In a new study, researchers have developed a novel generation of single-cell sequencing methods that has enabled them to expand on previous work identifying neuronal subtypes in the cerebral cortex and cerebellum. They were also able to further divide these neuronal subtypes into separate classes. The project stems from a previous study, published in Science, which identified 16 subtypes of neuron in the cerebral cortex. The landmark research was the first large scale mapping of gene activity in the human brain and provided a basis for understanding individual cell diversity. In the latest study, the researchers were also able to...