Researchers identify a novel pathway linked to cell death in Alzheimer’s disease

Lead researcher, Salvatore Oddo, of Arizona State University (AZ, USA), and colleagues have identified a new mechanism of cell death in Alzheimer’s disease (AD). These findings may help the development of future therapies targeting cell death within the disease. AD is characterized by a selective neuronal vulnerability resulting in severe neuronal loss and the progressive decline of various domains. To date, there is no cure for AD as the mechanisms which trigger the disease are still largely unknown. Within this study, Oddo and his team demonstrate the activation of necroptosis – a programmed form of necrosis (cell death), which has...