Switching off this ‘master regulator’ could protect the brain from Parkinson’s-related damage

Written by Sharon Salt, Senior Editor

In what is reported to be the first study of its kind, researchers have identified that switching off a particular ‘master regulator’ could protect the brain from Parkinson’s-related damage such as neurodegeneration and inflammatory damage. The results have been published in Nature Neuroscience and provide a novel avenue for developing therapies that preserve vulnerable brain cells in Parkinson’s disease. “One of the biggest challenges in treating Parkinson’s, other than the lack of therapies that impede disease progression, is that the disease has already laid waste to significant portions of the brain by the time it is diagnosed,” explained senior author...

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