Targeting microglia proliferation to treat neuropathic pain

Written by Lauren Pulling, Editor

Researchers at Rutgers University (NJ, USA) have demonstrated neuropathic pain could be reduced by targeting microglia proliferation. Although previous research has indicated a role for microglia in neuropathic pain, this is the first study to identify the specific contribution of these cells towards the pain condition, and opens a new avenue for the development of novel neuropathic pain treatments. “The general thought has been that [microglia] are supposed to be beneficial in the nervous system under normal conditions” explained Long-Jun Wu, Rutgers University. “But, in fact, in those with this neuropathic pain these cells… have proliferated and instead become toxic.”...

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