tRNAs: a blood-based biomarker for predicting seizures?

Written by Siobhan Bennett (Future Science Group)

‘Credit: Maxwell Photography’

A promising new study could provide an early warning system to enable people with epilepsy to know when they are at risk of having a seizure. Diagnosis of epilepsy is complex and challenging. Research led by FutureNeuro (Dublin, Ireland), hosted at the Royal College of Surgeons in Ireland (RCSI), has identified a unique molecular pattern within the blood before seizures happen. The results of the study have been published in the Journal of Clinical Investigation. When cells are stressed, this causes tRNA splicing to occur and results in a high level of tRNA within the blood. In this instance, this...

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