Jeffrey Iliff: glymphatics, Alzheimer’s and future directions

Written by Lauren Pulling, Editor

In October 2017 we had the pleasure of attending ‘Clearing the brain: protein clearance in neurodegenerative disease’, a 1-day symposium organized by the Leonard Wolfson Experimental Neurology Centre (LWENC) at University College London (UCL; London, UK). The event saw researchers and clinicians from across the world come together to share the latest research and debate the future of the field, with topics spanning perivascular clearance, fluid biomarkers, glymphatics, lymphatics, and a lively panel discussion.
In our final video recorded at the event, we speak to Jeffrey Iliff, Associate Professor at Oregon Health and Science University, OR, USA. Jeff and colleagues are carrying out pivotal work on glymphatics – the study of the functional waste clearance pathway in the CNS. Jeff tells us about his work, how dysfunction in the glymphatic system could contribute to Alzheimer’s disease, and how our growing knowledge in this area could be harnessed to develop new disease-modifying treatments for neurodegenerative diseases.

Want to find out more about the event? Catch up on our highlights in our Twitter Moment, plus have a look at our interviews with other speakers from the event:

You can also find out more about LWENC, dementia research at UCL and the event itself via the links below:




  1. Neuro Central