Neurology Central

SfN 2018: Day 3 Update

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Video highlight

Today’s news

SfN18: Can animal models offer an insight into human opioid addiction, withdrawal and relapse behaviors?

Pick of the posters

  • Jasarevic E, Hantsoo L, Howard CD, Weinkopff T, Epperson CN, Bale TL. The pregnancy gut microbiome as a translational biomarker of maternal adversity and offspring immune programming. This poster mentioned how the maternal microbiota are novel models of transmission of the early prenatal stress phenotype, involving alterations to bacterial assembly, host and gut microbiota metabolism, and substrate availability necessary for normal development. The researchers stated how transfer of stress altered maternal vaginal microbiota may reveal a novel mechanism whereby early prenatal stress exposure could reprogram the fetal gut environment. They concluded that maternal gut microbiota are sensitive to psychological stress experience; childhood adversity has lasting effects on the gut microbiome in pregnant women; and that the microbiome is readily accessible and may be a biomarker of maternal-fetal health.
  • Liu S, Parvizi J. Pathological cortical regions in patients with refractory epilepsy display normal physiological responses during cognitive tasks. In this study, the investigators explored the presence or absence of stimulus-locked physiological responses in a clerical epileptic tissue and determined its relationship with ongoing epileptic activities. They concluded that in patients with non-lesional neurocortical epilepsies, the cognitive reserve function of epileptic tissue is significant. They also report that pathological high-frequency oscillations and task-induced high-frequency broadband from the same cortical tissue exhibit different temporal characteristics, and can be reliably distinguished by using a combination of computational features. In addition to this, they mention that there may exist a causal relationship between the pathological high-frequency oscillations and functional high-frequency broadband responses: the stimulus high-frequency oscillations occurring shortly before the presentation of stimulus are more associated with the absence of high-frequency broadband responses.
  • Vanessa Chan TM, Alain C. Neural indices of auditory reflective attention in word-in-noise identification. The investigators in this research presented that separate patterns of neural activity emerged for the identification of a word-in-noise when the contextual information is presented before and when the context is given after the fact. The posterior pattern of activity during the After-Cue condition, as defined by the R-U contrast in distributed source modeling, suggested a parietal cortical involvement as implicated by the AtoM model. Future plans for this research include source-space modeling and extraction of data for functional connectivity analysis using phase transfer entropy.

Picture of the day

If you have a cool suggestion for what this octopus’ name should be, then let our Editor (Sharon Salt) know and you could win a free tote bag!

Today at our booth

Did you know… we’re on the lookout for regular contributors to our website? We’re also looking for exciting content to feature on our website and would be thrilled to hear from you if you haven’t stopped by already! If you don’t catch our Editor, Sharon Salt, at the booth, then please leave your business card or email address at booth #3526 and she’ll be able to get in touch with you. Alternatively, you can contact our Editor via email by clicking here.

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