Neurology Central

AAIC 2019: Why is Alzheimer’s disease more prevalent in women? Sex-specific differences reported

Four new papers presented at the Alzheimer’s Association International Conference 2019 (AAIC; 14–18 July, Los Angeles, CA, USA) have found variances in the risk and progression of Alzheimer’s disease (AD) between men and women, including sex-specific differences in the spread of tau protein, risk genes and levels of brain glucose metabolism.

According to the Alzheimer’s Association (IL, USA), two-thirds of people living with AD in the USA are women. Recent studies presented at AAIC 2019 reveal how sex-specific differences could help to explain why more women than men have Alzheimer’s.

“The majority of people living with Alzheimer’s are women and it’s imperative we understand why,” commented Maria C Carrillo, Alzheimer’s Association Chief Science Officer. “The research reported today at AAIC gets us one step closer to answering that question by identifying specific biological and social reasons why Alzheimer’s is different in men and women.”

One abstract, presented by researchers from the University of California Los Angeles (CA, USA), reported that women who participated in paid employment experienced slower rates of late-life memory decline compared with women who had never worked.

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