‘Smoldering’ spots: a hallmark for progressive multiple sclerosis?

Researchers have indicated that dark-rimmed spots that represent ongoing, ‘smoldering’ inflammation (also referred to as chronic active lesions) may be a hallmark for more aggressive and disabling forms of multiple sclerosis (MS). By using brain scans, the investigators were able to detect which patients were more susceptible to the aggressive forms of the disease. Daniel Reich (NIH National Institute of Neurological Disorders and Stroke, MD, USA), senior author of the study, stated that the more chronic active lesions a person has, the greater their chances are at experiencing this type of MS. The results have been published in JAMA Neurology....