Could circadian rhythms influence immune response efficiency in mice?

Written by Ebony Torrington (Future Science Group)

A research team, led by Nicolas Cermakian and Nathalie Labrecque at McGill University (Quebec, Canada), has demonstrated that circadian rhythms in mice could control the extent of CD8 T-cell response to antigen presentation by dendritic cells. The CD8 T cells’ circadian clock is essential for circadian regulation and the cells have been found to be stimulated depending on the time of day. The research has been published in Proceedings of the National Academy of Sciences of the United States of America. The research team investigated the CD8 T cells’ response to antigens presented by dendritic cells. Vaccination with dendritic cells...

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