Novel enzyme pathway implicated in ALS

Written by Rhiannon Finnie

Researchers from the University of Missouri (MO, USA) have recently identified a potential therapeutic target for amyotrophic lateral sclerosis (ALS) that has the potential to lessen the severity and progression of the disease. Recently published in Cell Reports, the research reports this same enzyme pathway could also be target for recovery of patients who have suffered stroke and other neurological diseases. Shinghua Ding, co-author of the study and associate professor of bioengineering and investigator in the Dalton Cardiovascular Research Center (MO, USA) explained:  “Our previous studies indicated that an enzyme known as nicotinamide phosphoribosyltransferase (NAMPT) is primarily expressed in the...

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