Patterns of brain activity could predict early Alzheimer’s symptoms in mice

Written by Heather Jones, Assistant Editor

Researchers at Gladstone Institutes (CA, USA) have been investigating the cerebral activity associated with Alzheimer’s disease. In a new study published in Cell Reports, they demonstrate that particular patterns of brain activity could indicate whether a young mouse will develop Alzheimer’s prior to any noticeable signs of memory loss. In previous research, senior author of the study Yadong Huang (Gladstone Institutes) and his team investigated sharp-wave ripples (SWRs), which are brain patterns that play a direct role in spatial learning and memory formation. They occur when the brain of a mouse or human replays a recent memory of moving through...

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