Polymer shows promise in treating Huntington’s disease
A polymer has been developed to optimize the use of a peptide to treat Huntington’s disease in mice.
Huntington’s disease is a devastating condition with no cure or treatments to slow its progression. Now, researchers led by Nathan Gianneschi (Northwestern University, IL, USA) and Xin Qi (Case Western Reserve University, OH, USA) have developed a protein-like polymer that helps prolong an active peptide’s survival and delivers it to the brain. The polymer has shown promise in preventing protein aggregation in a mouse model of Huntington’s and could be a helpful tool in the delivery of active peptides in other diseases.
