Scientists discover ‘silent seizures’ in Alzheimer’s disease patients

Written by Amy Bamford

Scientists from Bayor College of Medicine (TX, USA) and Massachusetts General Hospital and Harvard Medical School (MA, USA) have observed clinically silent hippocampal seizures in two Alzheimer’s patients with no previous history of seizures. The results, published in Nature Medicine, show that episodic seizure-like electrical activity is detected during sleep, a period when memories are consolidated. These novel findings could open up new research avenues for further understanding and potential treatment of Alzheimer’s disease (AD). Jeffrey Noebels, Bayor College of Medicine, explained:  “About 10 years ago, we were surprised to find ‘silent seizures’ in mouse models of AD, “When we...

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