SfN17: New insights into the impacts of stress – epigenetics and neurogenesis

Written by Martha Powell

New research presented at the Society for Neuroscience’s annual meeting, Neuroscience 2017, (11–15 November 2017, Washington DC, USA) has uncovered mechanisms by which stress impacts the brain, highlighting potential targets for reducing these effects. In a study assessing sperm microRNA, researchers have discovered that the stress a father experiences can alter how his sperm matures, impacting the subsequent offspring’s brain development. The team developed an in vitro model where they administered stress hormones to cultured cells from the caput epididymis, observing that the cells responded by altering the microRNA content in their vesicles, which in vivo would go on to...

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