SfN18: Exosomes could have wide-ranging and long-term effects in the brain and body

Written by Ebony Torrington, Future Science Group

Three new papers presented at SfN Neuroscience 2018 (3–7 November, San Diego, CA, USA), have found that extracellular vesicles transported between cells have long-term and wide-ranging effects in the body, and some extracellular vesicles released from the brain into the blood could also provide a method of diagnosis for neurodegenerative diseases (ND) such as Parkinson’s disease. Jason Shepherd, senior author at the University of Utah (UT) and colleagues have found the neurological Arc protein to express retrovirus-like properties, such as accumulation into capsids that are released extracellularly and deliver RNA and proteins to nearby cells. ND’s such as Alzheimer’s disease...

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