Successful autoantigen–coupling in mouse model may aid in the treatment of multiple sclerosis

Written by Courtney Johnson

Findings from research at the University of Florida (FL, USA), published recently in the Journal of Immunology Research, demonstrate that autoantigens of myelin coupled with spleen cells and transfused into mice, may prevent the development of experimental autoimmune encephalomyelitis (EAE) as well as reverse the early stages of the disease. Researchers believe that the results are promising, with potential for application in clinical trials utilizing autoantigen therapy in humans with multiple sclerosis (MS). MS is an autoimmune disorder of the CNS that involves inflammation of the myelin of the optic, brain and spinal cord nerves. Such inflammation results in compromised...

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