Neurology Central

Frontiers in TBI 2019: highlights from the Editor

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This year we had the pleasure of attending the Frontiers in Traumatic Brain Injury (Frontiers in TBI) conference, which took place on 16 September 2019 (University College London, UK). The one-day conference showcased the exciting developments in the world of TBI research, including machine learning, criminality, big data, digital technology and much more. In this report, we’ll share with you some of our key highlights and takeaway messages from the conference.


Neuropathological aspects of TBI

One of the themes that stood out to us the most was the session on neuropathological aspects of TBI, which included talks on neurodegeneration, imaging in tau and preclinical models of tau propagation.

The mismatched mishmash of neurodegeneration in TBI

Starting off the session with a tongue-twisting title, we heard from William Stewart (University of Glasgow, UK) on the mismatched mishmash of neurodegeneration in TBI. In chronic traumatic encephalopathy (CTE), it is well known that pathognomonic lesions of the disease consist of p-tau aggregates within neurons and astrocytes. Additionally, cell processes around small vessels are distributed in patchy and irregular patters. What remains uncertain, however, is what seeing tau actually means in this instance.

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