Molecular imaging of tau pathology after traumatic brain injury with Nikos Gorgoraptis

Written by Sharon Salt (Senior Editor) & Kimberley Ndungu (Future Science Group)

Last year, researchers from Imperial College London (UK) published a study indicating that flortaucipir PET could be used as a potential diagnostic tool for neurodegenerative conditions linked to tau protein accumulation. Within their study, they also discovered that tau protein tangles were present in the brains of individuals who had experienced a single, severe head injury.

At the Frontiers in Traumatic Brain Injury (TBI) Conference (16 September, London, UK), we spoke with first author of the publication, Nikos Gorgoraptis (Imperial College London), to hear more about molecular imaging of tau pathology after TBI. Nikos also discusses the limitations of using molecular imaging, such as PET scans, as an assessment method after TBI and what can be done to overcome these obstacles.

Questions on molecular imaging of tau pathology:

00:22 – Why is this area of research an unmet need?

02:36 – What is the clinical importance of understanding tau pathology after traumatic brain injury?

04:10 – What are the limitations of using molecular imaging, such as PET scans, as an assessment method after TBI? And what do you think needs to be done to overcome these challenges?

05:36 – Lastly, what predictions do you have for the future of this field?

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Disclaimer
The opinions expressed in this interview are those of the interviewee and do not necessarily reflect the views of Neuro Central or Future Science Group.