Could tau protein accumulation be prevented by removing β-arrestin-2 oligomers?

Written by Alice Bough (Future Science Group)

Researchers from the University of South Florida (USF; FL, USA) have discovered that β-arrestin-2 oligomerization may disrupt the process by which neurotoxic tau proteins are removed from the brain.   The authors of the study, published in the Proceedings of the National Academy of Sciences, suggest that β-arrestin-2 oligomers could be a new target for the prevention and treatment of dementia. While the role of monomers of β-arrestin-2 is considered to be in regulating neurotransmitter receptors, little is known about the functions of oligomers of β-arrestin-2. To analyze whether either form of β-arrestin-2 has a role in the development of...

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