New study suggests the need for early detection of Alzheimer’s disease pathology

Written by Sharon Salt, Editor

According to a longitudinal study, researchers have suggested that anti-amyloid therapies would be most effective before individuals reach the threshold for preclinical Alzheimer’s disease (AD) – long before the first signs of memory problems appear. Current approaches to the early detection of AD rely upon classifying individuals as ‘positive’ or ‘negative’ for biomarkers related to β-amyloid. However, according to recent research, the rate at which β-amyloid accumulates into sticky plaques associated with AD is already slowing by the time a patient would be considered to have preclinical AD. In a recently published study in JNeurosci, researchers investigated the relationship between...

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