‘Thrill-seeking’ microglia reveal sex-specific differences in mice

In a recent study published in Cell Reports, researchers from the Max Delbrück Center for Molecular Medicine (MDC; Berlin, Germany) have reported sex-specific differences in microglia in mice. They believe that these findings could potentially change how we treat neurological diseases. Using brain slices and isolated cells, Susanne Wolf (MDC) and colleagues conducted a study on the structure and function of microglia. Their findings revealed that the brains of male mice contain more microglia, and that the cell bodies of brain immune cells in males were larger than their female counterparts. In addition to this, the scientists also determined not...